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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3D19
All Species:
21.21
Human Site:
S275
Identified Species:
58.33
UniProt:
Q5HYK7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5HYK7
NP_001009555.3
790
86525
S275
C
L
H
E
D
P
Q
S
P
P
P
L
P
A
E
Chimpanzee
Pan troglodytes
XP_001152369
787
86103
S272
C
L
H
E
D
P
Q
S
P
P
P
L
P
A
E
Rhesus Macaque
Macaca mulatta
XP_001082920
787
85765
S272
C
L
H
E
D
P
Q
S
P
P
P
L
P
A
E
Dog
Lupus familis
XP_539763
786
85616
S271
C
L
H
E
D
P
Q
S
P
P
P
L
P
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91X43
789
86058
S274
C
L
H
E
E
P
Q
S
P
P
P
L
P
A
E
Rat
Rattus norvegicus
Q9WVE9
1217
137136
V341
S
S
E
D
E
Q
Q
V
E
K
K
L
P
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511455
557
60881
L77
S
V
E
R
A
R
A
L
E
S
G
Q
P
G
N
Chicken
Gallus gallus
XP_420444
779
86598
S271
S
L
D
E
I
P
H
S
P
P
P
L
P
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793803
946
99809
G276
N
V
T
A
E
E
I
G
H
A
T
N
F
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
97
84.1
N.A.
78.3
20.2
N.A.
47.8
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
98.9
98.2
89.6
N.A.
86
33.3
N.A.
56.4
53.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
20
N.A.
6.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
12
0
0
12
0
0
0
67
0
% A
% Cys:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
45
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
23
67
34
12
0
0
23
0
0
0
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
12
0
0
12
0
% G
% His:
0
0
56
0
0
0
12
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
12
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% K
% Leu:
0
67
0
0
0
0
0
12
0
0
0
78
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% N
% Pro:
0
0
0
0
0
67
0
0
67
67
67
0
89
0
0
% P
% Gln:
0
0
0
0
0
12
67
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
12
0
0
0
0
0
67
0
12
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
23
% T
% Val:
0
23
0
0
0
0
0
12
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _